Setyr worked example — TP-12 Tablet Press — Tooling Change and Containment Isolation Not approved for use. Version 1 · 2026-09-08
Worked example only — your site must author, review and approve its own
procedure under 29 CFR 1910.147(c)(4). setyr.com/procedures
TP-12 Tablet Press — Tooling Change and Containment Isolation
Pharmaceutical
Turret tooling change on a high-containment rotary tablet press handling a potent compound. Covers compression pre-load, turret rotation, wash-in-place lines, and the pressure cascade that must hold throughout because it is the containment.
This is a worked example, not a procedure you can adopt. It describes equipment that does not exist, with illustrative tag numbers.
29 CFR 1910.147(c)(4) requires the employer to develop, document and
utilise energy control procedures specific to their own machines, and (c)(6)
requires the employer to inspect those procedures periodically. Neither duty
can be delegated to a vendor or discharged by this document.
Isolation points
| # | Tag (illustrative) | Type | Disposition | What it does and why | Dwell |
|---|---|---|---|---|---|
| 10 | TP-12-MAIN | Disconnect | Isolate & lock | Press main disconnect at the machine panel. Caution: The turret carries residual rotation. Electrical isolation does not stop it turning. Open, lock, prove dead at the load side. | — |
| 20 | TP-12-TURRET | Block | Apply & verify | Turret drive brake and the manual barring point. Caution: A turret barred by hand for tooling access rotates under the weight of the upper punches once released. Engage the turret brake and confirm the barring tool is removed. Brake must be ENGAGED. | — |
| 30 | TP-12-COMP | Bleed | Isolate & lock | Compression roll pre-load, hydraulically pre-tensioned to compression force. Caution: The rolls hold tens of kilonewtons of pre-load at rest, and hands go directly into that zone during a tooling change. Release the compression pre-load at the release valve and confirm the force display reads zero before entering the compression zone. | 180s |
| 40 | TP-12-HYD | Disconnect | Isolate & lock | Hydraulic power pack supplying compression pre-load and the turret clamp. Caution: Bleeding after isolating removes the path that could re-apply pre-load. Open and lock the power pack disconnect, then bleed the accumulator. | 120s |
| 50 | TP-12-FEED | Valve | Isolate & lock | Powder feed frame drive and the hopper slide valve. Caution: An open hopper slide releases potent powder into the open machine when the turret is barred. Close the hopper slide, lock it, and isolate the feed frame drive. | — |
| 60 | TP-12-WIP | Valve | Isolate & lock | Wash-in-place spray header inside the compression chamber. Caution: A WIP cycle triggered with the chamber open sprays hot detergent and potent residue into the room. Close and lock the WIP supply valve at the skid. | — |
| 70 | TP-12-DEDUST | Disconnect | Isolate & lock | De-duster and tablet transfer chute drive. Open and lock. | — |
| 80 | TP-12-AIR | Valve | Isolate & lock | Machine compressed air to the turret clamp, punch lubrication and inflatable door seals. Caution: Inflatable containment seals deflate on loss of air. Bleed only once the containment strategy for the open machine is agreed. Close the supply, lock, and bleed the machine air header. | 90s |
| 90 | TP-12-SAFE-CH | Block | Apply & verify | Safe-change bag-in bag-out filter housing on the containment extract. Caution: A breached housing releases collected potent dust into the technical area behind the machine. Confirm the safe-change housing is intact and not breached before work begins. | — |
| 100 | TP-12-ISO-DP | Breaker | KEEP ENERGISED | Containment pressure cascade holding the machine negative to the room. Caution: The cascade is what keeps a potent compound inside the machine. Losing it during a tooling change exposes the operator and the suite. Do NOT isolate. Confirm the differential pressure is within limits and alarming before the machine is opened. | — |
| 110 | TP-12-DUST | Breaker | KEEP ENERGISED | Dust extraction from the compression zone to the containment filter. Caution: Extraction and the pressure cascade work together. Isolating either defeats both. Do NOT isolate. Confirm extraction flow before opening the compression chamber. | — |
| 120 | TP-12-ROOM-HVAC | Breaker | KEEP ENERGISED | Room HVAC serving the containment suite. Caution: Isolating room HVAC to work on the machine collapses the suite cascade and pushes contamination toward the corridor. Do NOT isolate. Room air changes must continue for the duration of the work. | — |
What your site must supply
- Your own asset and isolation-point tag numbers. The tags shown are illustrative and refer to equipment that does not exist.
- The actual location of every disconnect, valve and vent on your equipment.
- Measured stored-energy magnitudes and the dwell time required to dissipate them.
- Your verification method for each point, and who is authorised to perform it.
- Any additional energy sources present on your equipment and absent here.
Authorship and validation
This example was authored by Setyr for domain validation. It is not derived from any customer's controlled documents. It illustrates the elements 29 CFR 1910.147(c)(4)(ii) requires a procedure to contain — it does not certify compliance, which is a property of an employer's programme rather than of any document.